Motif ID: TFAP2{A,C}.p2

Z-value: 1.887


Transcription factors associated with TFAP2{A,C}.p2:

Gene SymbolEntrez IDGene Name
TFAP2A 7020 transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TFAP2C 7022 transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TFAP2Achr6_-_104152170.485.1e-14Click!
TFAP2Cchr20_+_55204307-0.063.7e-01Click!


Activity profile for motif TFAP2{A,C}.p2.

activity profile for motif TFAP2{A,C}.p2


Sorted Z-values histogram for motif TFAP2{A,C}.p2

Sorted Z-values for motif TFAP2{A,C}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TFAP2{A,C}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_+_236403290 37.114 AGAP1
ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
chr2_+_236402948 25.307 AGAP1
ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
chr15_-_48937068 25.103 FBN1
fibrillin 1
chr17_-_74707000 23.220 NM_001008528
NM_001008529
NM_198530
MXRA7


matrix-remodelling associated 7


chr17_-_7197811 21.344 YBX2
Y box binding protein 2
chr16_+_226678 20.902 NM_000558
HBA1
HBA2
hemoglobin, alpha 1
hemoglobin, alpha 2
chr17_-_7197896 20.513 YBX2
Y box binding protein 2
chr17_-_7197866 19.517 NM_015982
YBX2
Y box binding protein 2
chr7_-_129251465 19.396


chr16_+_222845 17.520 NM_000517
HBA1
HBA2
hemoglobin, alpha 1
hemoglobin, alpha 2
chr11_-_65640199 17.337 NM_016938
EFEMP2
EGF containing fibulin-like extracellular matrix protein 2
chr8_-_48650683 15.834 CEBPD
CCAAT/enhancer binding protein (C/EBP), delta
chr9_-_112083005 15.282 NM_018424
NM_019114
EPB41L4B

erythrocyte membrane protein band 4.1 like 4B

chr9_+_137533643 13.681 NM_000093
COL5A1
collagen, type V, alpha 1
chr13_+_110959592 12.912 NM_001846
COL4A2
collagen, type IV, alpha 2
chr3_-_124774735 12.821 NM_020733
HEG1
HEG homolog 1 (zebrafish)
chr2_-_218843541 12.692 TNS1
tensin 1
chr17_-_74707066 12.489 MXRA7
matrix-remodelling associated 7
chr3_+_51428720 12.371 RBM15B
RNA binding motif protein 15B
chr15_+_96873845 11.858 NM_021005
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr4_-_57976355 11.801 IGFBP7
insulin-like growth factor binding protein 7
chr1_-_23857284 11.671 E2F2
E2F transcription factor 2
chr9_+_35605275 11.622 NM_006285
TESK1
testis-specific kinase 1
chr13_-_110959441 10.944 NM_001845
COL4A1
collagen, type IV, alpha 1
chr8_-_48650703 10.765 NM_005195
CEBPD
CCAAT/enhancer binding protein (C/EBP), delta
chr17_+_59477473 10.658 TBX2
T-box 2
chr7_+_45614179 10.648 ADCY1
adenylate cyclase 1 (brain)
chr3_-_45267068 10.495 TMEM158
transmembrane protein 158 (gene/pseudogene)
chr6_+_37787266 10.473 NM_021943
ZFAND3
zinc finger, AN1-type domain 3
chr16_+_28834407 10.412 NM_007245
NM_145714
NM_148414
NM_148415
NM_148416
ATXN2L




ataxin 2-like




chr7_-_158622184 10.297 ESYT2
extended synaptotagmin-like protein 2
chr22_-_19511777 10.235 CLDN5
claudin 5
chr18_-_51750460 10.217 MBD2
methyl-CpG binding domain protein 2
chr17_+_18128868 10.163 NM_004140
LLGL1
lethal giant larvae homolog 1 (Drosophila)
chr16_+_28834372 10.031 ATXN2L
ataxin 2-like
chr19_+_2096792 9.981 NM_001031735
NM_001039846
IZUMO4

IZUMO family member 4

chr1_+_46269283 9.975 NM_015112
MAST2
microtubule associated serine/threonine kinase 2
chr2_+_241375030 9.974 NM_002081
GPC1
glypican 1
chr19_-_18717467 9.901 CRLF1
cytokine receptor-like factor 1
chr2_+_241938254 9.852 NM_001080437
SNED1
sushi, nidogen and EGF-like domains 1
chr9_+_35605339 9.822 TESK1
testis-specific kinase 1
chr7_-_50132789 9.646 NM_001159878
NM_007009
ZPBP

zona pellucida binding protein

chr3_+_51428698 9.604 NM_013286
RBM15B
RNA binding motif protein 15B
chr16_+_28834565 9.593 ATXN2L
ataxin 2-like
chr5_-_178772328 9.484 ADAMTS2
ADAM metallopeptidase with thrombospondin type 1 motif, 2
chr19_-_18717631 9.448 NM_004750
CRLF1
cytokine receptor-like factor 1
chr3_-_48885217 9.405 PRKAR2A
protein kinase, cAMP-dependent, regulatory, type II, alpha
chr12_-_106641675 9.251 NM_006825
CKAP4
cytoskeleton-associated protein 4
chr6_+_37787592 9.232 ZFAND3
zinc finger, AN1-type domain 3
chr17_+_74864427 9.191 NM_001199172
NM_144677
MGAT5B

mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B

chr6_+_41040891 9.162 NFYA
nuclear transcription factor Y, alpha
chr16_+_28834360 9.116 ATXN2L
ataxin 2-like
chr17_+_36507708 9.063 NM_014598
SOCS7
suppressor of cytokine signaling 7
chr10_+_11784355 9.028 NM_024693
ECHDC3
enoyl CoA hydratase domain containing 3
chr3_-_48885028 9.021 PRKAR2A
protein kinase, cAMP-dependent, regulatory, type II, alpha
chr19_+_40697516 9.000 NM_002446
MAP3K10
mitogen-activated protein kinase kinase kinase 10
chr16_+_2588000 8.966 PDPK1
3-phosphoinositide dependent protein kinase-1
chr9_-_35689902 8.921 NM_003289
NM_213674
TPM2

tropomyosin 2 (beta)

chr18_-_74207145 8.870 NM_014643
ZNF516
zinc finger protein 516
chr10_-_32636134 8.845 EPC1
enhancer of polycomb homolog 1 (Drosophila)
chr4_-_5894695 8.825 NM_001014809
CRMP1
collapsin response mediator protein 1
chr9_+_35605449 8.790 TESK1
testis-specific kinase 1
chr2_+_121103670 8.786 NM_002193
INHBB
inhibin, beta B
chr19_-_46389307 8.765 NM_015649
IRF2BP1
interferon regulatory factor 2 binding protein 1
chr2_+_26915390 8.753 NM_002246
KCNK3
potassium channel, subfamily K, member 3
chr11_+_46299554 8.753 CREB3L1
cAMP responsive element binding protein 3-like 1
chr17_-_79818514 8.727 NM_000918
P4HB
prolyl 4-hydroxylase, beta polypeptide
chr14_-_77787023 8.708 NM_013382
POMT2
protein-O-mannosyltransferase 2
chr22_+_33197744 8.707 TIMP3
TIMP metallopeptidase inhibitor 3
chr2_-_224903933 8.694 NM_001136528
NM_006216
SERPINE2

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2

chr9_+_35605614 8.655 TESK1
testis-specific kinase 1
chr5_-_178772430 8.548 NM_014244
NM_021599
ADAMTS2

ADAM metallopeptidase with thrombospondin type 1 motif, 2

chr3_-_38071030 8.539 NM_006225
PLCD1
phospholipase C, delta 1
chr6_+_41040687 8.497 NM_002505
NM_021705
NFYA

nuclear transcription factor Y, alpha

chr19_+_2096930 8.490 IZUMO4
IZUMO family member 4
chr1_+_52608045 8.476 NM_004799
NM_007323
NM_007324
ZFYVE9


zinc finger, FYVE domain containing 9


chr11_+_61197574 8.463 NM_017841
SDHAF2
succinate dehydrogenase complex assembly factor 2
chr2_-_73340058 8.455 RAB11FIP5
RAB11 family interacting protein 5 (class I)
chr10_-_99790346 8.442 CRTAC1
cartilage acidic protein 1
chr7_-_45960738 8.405 NM_000598
NM_001013398
IGFBP3

insulin-like growth factor binding protein 3

chr3_-_45267620 8.346 TMEM158
transmembrane protein 158 (gene/pseudogene)
chr19_-_18717577 8.342 CRLF1
cytokine receptor-like factor 1
chr4_-_2263808 8.339 MXD4
MAX dimerization protein 4
chr6_+_151561653 8.234 AKAP12
A kinase (PRKA) anchor protein 12
chr11_+_117070039 8.189 NM_001001522
NM_003186
TAGLN

transgelin

chr2_+_176972005 8.186 NM_021192
HOXD11
homeobox D11
chr21_+_47531369 8.154 COL6A2
collagen, type VI, alpha 2
chr18_+_55102777 8.153 NM_004852
ONECUT2
one cut homeobox 2
chr6_+_43738757 8.070 VEGFA
vascular endothelial growth factor A
chr3_-_129325175 8.065 NM_015103
PLXND1
plexin D1
chr7_-_140624280 8.049 NM_004333
BRAF
v-raf murine sarcoma viral oncogene homolog B1
chr2_-_45236521 7.989 NM_016932
SIX2
SIX homeobox 2
chr13_+_98795710 7.938 FARP1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr4_-_2263706 7.918 NM_006454
MXD4
MAX dimerization protein 4
chrX_+_135229536 7.884 NM_001159702
NM_001159703
NM_001449
FHL1


four and a half LIM domains 1


chr10_-_128077011 7.854 ADAM12
ADAM metallopeptidase domain 12
chr19_-_5340700 7.787 NM_002850
NM_130853
NM_130854
NM_130855
PTPRS



protein tyrosine phosphatase, receptor type, S



chr3_+_14989076 7.759 NM_003298
NR2C2
nuclear receptor subfamily 2, group C, member 2
chr6_+_43139201 7.725 SRF
serum response factor (c-fos serum response element-binding transcription factor)
chr11_+_12132063 7.691 NM_014632
MICAL2
microtubule associated monoxygenase, calponin and LIM domain containing 2
chr2_-_101767714 7.671 NM_001102426
TBC1D8
TBC1 domain family, member 8 (with GRAM domain)
chr22_+_33197678 7.666 TIMP3
TIMP metallopeptidase inhibitor 3
chr2_-_97303983 7.614 KANSL3
KAT8 regulatory NSL complex subunit 3
chr16_+_22825806 7.603 NM_006043
HS3ST2
heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr16_+_4784261 7.581 NM_139170
C16orf71
chromosome 16 open reading frame 71
chr8_+_37654406 7.578 GPR124
G protein-coupled receptor 124
chr9_+_133320093 7.546 NM_000050
NM_054012
ASS1

argininosuccinate synthase 1

chr5_+_172483285 7.545 NM_001168393
NM_001168394
NM_153607
C5orf41


chromosome 5 open reading frame 41


chr7_-_158622202 7.493 NM_020728
ESYT2
extended synaptotagmin-like protein 2
chr19_-_15311773 7.448 NM_000435
NOTCH3
notch 3
chrX_+_153237990 7.431 NM_003492
TMEM187
transmembrane protein 187
chrX_-_133119475 7.425 GPC3
glypican 3
chr16_+_2588021 7.403 PDPK1
3-phosphoinositide dependent protein kinase-1
chr10_-_79686279 7.371 NM_004747
DLG5
discs, large homolog 5 (Drosophila)
chr16_+_4784320 7.325 C16orf71
chromosome 16 open reading frame 71
chr22_+_20067732 7.302 NM_001190326
NM_022720
DGCR8

DiGeorge syndrome critical region gene 8

chr1_-_182360181 7.280 GLUL
glutamate-ammonia ligase
chr1_-_38512446 7.275 NM_002699
POU3F1
POU class 3 homeobox 1
chr3_+_71803200 7.273 NM_018971
GPR27
G protein-coupled receptor 27
chr4_-_8873453 7.246 NM_018942
HMX1
H6 family homeobox 1
chr21_-_28217272 7.229 ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr17_+_7211260 7.225 NM_001143761
EIF5A
eukaryotic translation initiation factor 5A
chr6_+_41040713 7.224 NFYA
nuclear transcription factor Y, alpha
chr4_-_57976516 7.219 IGFBP7
insulin-like growth factor binding protein 7
chr3_-_14988939 7.204 LOC100505641
uncharacterized LOC100505641
chr10_-_99790584 7.180 NM_001206528
NM_018058
CRTAC1

cartilage acidic protein 1

chr6_-_144329342 7.170 NM_001080952
NM_001080953
NM_001080954
NM_001080956
NM_002656
NM_006718
PLAGL1





HYMAI
pleiomorphic adenoma gene-like 1





hydatidiform mole associated and imprinted (non-protein coding)
chr8_+_30241943 7.165 NM_001008710
NM_001008711
NM_001008712
NM_006867
RBPMS



RNA binding protein with multiple splicing



chr5_-_168727715 7.155 NM_003062
SLIT3
slit homolog 3 (Drosophila)
chr16_-_2264776 7.153 NM_001042371
PGP
phosphoglycolate phosphatase
chr16_+_4784446 7.125 C16orf71
chromosome 16 open reading frame 71
chr17_-_15902907 7.120 NM_001042697
NM_001042698
ZSWIM7

zinc finger, SWIM-type containing 7

chr7_+_64498643 7.091 CCT6P3
chaperonin containing TCP1, subunit 6 (zeta) pseudogene 3
chr2_+_203499819 7.046 NM_173511
FAM117B
family with sequence similarity 117, member B
chr12_-_124457099 7.035 NM_025140
CCDC92
coiled-coil domain containing 92
chr1_+_6845381 6.991 NM_001195563
NM_001242701
NM_015215
CAMTA1


calmodulin binding transcription activator 1


chr1_+_20959946 6.991 NM_032409
PINK1
PTEN induced putative kinase 1
chr4_-_1166364 6.983 SPON2
spondin 2, extracellular matrix protein
chr10_-_128077062 6.980 ADAM12
ADAM metallopeptidase domain 12
chr2_-_73339911 6.944 RAB11FIP5
RAB11 family interacting protein 5 (class I)
chr2_-_183902747 6.943 NCKAP1
NCK-associated protein 1
chr3_-_53080038 6.930 NM_001005158
NM_016329
SFMBT1

Scm-like with four mbt domains 1

chr19_+_18942786 6.925 UPF1
UPF1 regulator of nonsense transcripts homolog (yeast)
chr13_-_77460432 6.923 NM_138444
KCTD12
potassium channel tetramerisation domain containing 12
chr2_-_220408264 6.916 NM_024536
CHPF
chondroitin polymerizing factor
chr19_+_589849 6.912 NM_001194
HCN2
hyperpolarization activated cyclic nucleotide-gated potassium channel 2
chr15_-_48937795 6.908 NM_000138
FBN1
fibrillin 1
chr9_+_133320247 6.894 ASS1
argininosuccinate synthase 1
chr20_-_32031425 6.890 NM_003098
SNTA1
syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component)
chr13_-_45150601 6.839 NM_001243799
NM_183422
TSC22D1

TSC22 domain family, member 1

chr22_-_20104695 6.834 TRMT2A
TRM2 tRNA methyltransferase 2 homolog A (S. cerevisiae)
chr12_-_56122748 6.819 CD63
CD63 molecule
chr11_+_65554504 6.813 NM_004561
OVOL1
ovo-like 1(Drosophila)
chr19_+_39833096 6.799 SAMD4B
sterile alpha motif domain containing 4B
chr6_+_43738177 6.785 VEGFA
vascular endothelial growth factor A
chr8_-_21966812 6.695 NM_024815
NUDT18
nudix (nucleoside diphosphate linked moiety X)-type motif 18
chr15_+_74218962 6.690 LOXL1
lysyl oxidase-like 1
chr17_+_59477710 6.687 TBX2
T-box 2
chr19_-_344778 6.675 NM_017550
MIER2
mesoderm induction early response 1, family member 2
chr14_-_75078669 6.674 NM_000428
LTBP2
latent transforming growth factor beta binding protein 2
chr12_+_53491448 6.651 IGFBP6
insulin-like growth factor binding protein 6
chr9_-_94186140 6.578 NM_005384
NFIL3
nuclear factor, interleukin 3 regulated
chr1_-_33430285 6.563 NM_001127361
NM_153341
RNF19B

ring finger protein 19B

chr19_+_15218141 6.562 NM_033025
SYDE1
synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chr11_+_65554566 6.554 OVOL1
ovo-like 1(Drosophila)
chr6_+_7108864 6.492 RREB1
ras responsive element binding protein 1
chr16_+_1203240 6.491 NM_001005407
NM_021098
CACNA1H

calcium channel, voltage-dependent, T type, alpha 1H subunit

chr19_+_50016490 6.489 FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr2_-_73340073 6.480 NM_015470
RAB11FIP5
RAB11 family interacting protein 5 (class I)
chr17_+_29421956 6.452 NF1
neurofibromin 1
chr5_-_171433605 6.442 FBXW11
F-box and WD repeat domain containing 11
chr7_+_44143945 6.423 NM_001129
AEBP1
AE binding protein 1
chr2_+_113033146 6.405 NM_198581
ZC3H6
zinc finger CCCH-type containing 6
chr11_-_66084501 6.386 NM_020404
CD248
CD248 molecule, endosialin
chr9_-_89562103 6.359 NM_002048
GAS1
growth arrest-specific 1
chr19_+_33685489 6.358 NM_002333
LRP3
low density lipoprotein receptor-related protein 3
chr2_-_97304060 6.352 KANSL3
KAT8 regulatory NSL complex subunit 3
chr15_+_84322809 6.345 NM_207517
ADAMTSL3
ADAMTS-like 3
chr17_+_64960754 6.323 NM_014405
CACNG4
calcium channel, voltage-dependent, gamma subunit 4
chr1_-_182360400 6.317 NM_001033056
GLUL
glutamate-ammonia ligase
chr5_+_170736287 6.313 NM_021025
TLX3
T-cell leukemia homeobox 3
chr17_+_59477169 6.299 NM_005994
TBX2
T-box 2
chr17_+_36861398 6.294 MLLT6
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr2_+_97481977 6.294 NM_017623
NM_199078
CNNM3

cyclin M3

chr3_-_14989399 6.293 LOC100505641
uncharacterized LOC100505641
chr8_+_37654395 6.276 NM_032777
GPR124
G protein-coupled receptor 124
chr16_-_4322695 6.276 TFAP4
transcription factor AP-4 (activating enhancer binding protein 4)
chr9_-_96717544 6.271 NM_021570
BARX1
BARX homeobox 1
chr19_+_33182689 6.268 NM_001105570
NUDT19
nudix (nucleoside diphosphate linked moiety X)-type motif 19
chr11_+_46299161 6.257 NM_052854
CREB3L1
cAMP responsive element binding protein 3-like 1
chr19_+_50016500 6.247 FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr10_+_99894426 6.233 C10orf28
chromosome 10 open reading frame 28
chr19_-_46295785 6.216 NM_004943
DMWD
dystrophia myotonica, WD repeat containing
chr13_+_37005966 6.213 NM_001111046
NM_001111047
CCNA1

cyclin A1

chr1_+_100818031 6.211 CDC14A
CDC14 cell division cycle 14 homolog A (S. cerevisiae)
chr16_+_2587951 6.201 NM_002613
NM_031268
PDPK1

3-phosphoinositide dependent protein kinase-1

chr17_-_74449272 6.138 NM_022066
UBE2O
ubiquitin-conjugating enzyme E2O
chr12_-_56122800 6.132 CD63
CD63 molecule
chr13_-_95364248 6.122 NM_007084
SOX21
SRY (sex determining region Y)-box 21
chr10_-_123357503 6.111 NM_000141
NM_001144917
NM_001144918
NM_001144919
NM_022970
FGFR2




fibroblast growth factor receptor 2





Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.19 2.91e-101 GO:0009987 cellular process
1.27 5.75e-62 GO:0044237 cellular metabolic process
1.21 1.13e-55 GO:0065007 biological regulation
1.32 1.85e-52 GO:0044260 cellular macromolecule metabolic process
1.22 5.97e-52 GO:0050789 regulation of biological process
1.23 2.14e-51 GO:0050794 regulation of cellular process
1.22 9.20e-51 GO:0008152 metabolic process
1.23 5.39e-46 GO:0044238 primary metabolic process
1.27 1.44e-42 GO:0043170 macromolecule metabolic process
1.34 2.22e-41 GO:0071840 cellular component organization or biogenesis
1.34 2.56e-41 GO:0016043 cellular component organization
1.36 2.28e-34 GO:0071841 cellular component organization or biogenesis at cellular level
1.36 5.66e-34 GO:0071842 cellular component organization at cellular level
1.32 5.64e-33 GO:0034641 cellular nitrogen compound metabolic process
1.37 1.10e-32 GO:0048522 positive regulation of cellular process
1.35 2.25e-32 GO:0048518 positive regulation of biological process
1.34 2.80e-32 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.31 1.21e-31 GO:0006807 nitrogen compound metabolic process
1.27 9.68e-30 GO:0023052 signaling
1.36 3.23e-29 GO:0048519 negative regulation of biological process
1.25 3.77e-29 GO:0051716 cellular response to stimulus
1.37 2.24e-28 GO:0048523 negative regulation of cellular process
1.46 4.61e-28 GO:0007399 nervous system development
1.36 4.65e-27 GO:0090304 nucleic acid metabolic process
1.28 8.00e-27 GO:0007165 signal transduction
1.33 1.11e-26 GO:0044267 cellular protein metabolic process
1.26 3.15e-26 GO:0032502 developmental process
1.29 4.80e-26 GO:0048856 anatomical structure development
1.29 1.16e-23 GO:0048731 system development
1.24 3.97e-23 GO:0019222 regulation of metabolic process
1.40 4.15e-23 GO:0006996 organelle organization
1.25 1.01e-22 GO:0007275 multicellular organismal development
1.25 2.68e-22 GO:0031323 regulation of cellular metabolic process
1.31 3.38e-21 GO:0044249 cellular biosynthetic process
1.52 4.24e-21 GO:0022008 neurogenesis
1.40 8.45e-21 GO:0009653 anatomical structure morphogenesis
1.29 1.16e-20 GO:0009058 biosynthetic process
1.25 2.76e-20 GO:0060255 regulation of macromolecule metabolic process
1.26 4.31e-20 GO:0019538 protein metabolic process
1.43 5.54e-20 GO:0009893 positive regulation of metabolic process
1.24 6.96e-20 GO:0080090 regulation of primary metabolic process
1.52 1.54e-19 GO:0048699 generation of neurons
1.35 3.77e-19 GO:0016070 RNA metabolic process
1.44 4.80e-19 GO:0010604 positive regulation of macromolecule metabolic process
1.35 2.91e-18 GO:0009059 macromolecule biosynthetic process
1.35 5.41e-18 GO:0034645 cellular macromolecule biosynthetic process
1.42 9.75e-18 GO:0031325 positive regulation of cellular metabolic process
1.30 1.85e-17 GO:0065008 regulation of biological quality
1.22 2.71e-17 GO:0051179 localization
1.47 4.05e-17 GO:0048468 cell development
1.30 4.20e-17 GO:0030154 cell differentiation
1.44 4.81e-17 GO:0032268 regulation of cellular protein metabolic process
1.39 4.85e-17 GO:0051641 cellular localization
1.34 5.78e-17 GO:0023051 regulation of signaling
1.43 8.54e-17 GO:0051246 regulation of protein metabolic process
1.30 1.06e-16 GO:0048869 cellular developmental process
1.32 1.42e-16 GO:0010467 gene expression
1.32 2.47e-16 GO:0006464 protein modification process
1.53 6.78e-16 GO:0030182 neuron differentiation
1.30 7.31e-16 GO:0043412 macromolecule modification
1.53 3.42e-15 GO:0007167 enzyme linked receptor protein signaling pathway
1.42 5.31e-15 GO:0006793 phosphorus metabolic process
1.42 5.31e-15 GO:0006796 phosphate metabolic process
1.47 2.21e-14 GO:0031399 regulation of protein modification process
1.46 2.52e-14 GO:0033554 cellular response to stress
1.34 2.82e-14 GO:0009966 regulation of signal transduction
1.40 1.29e-13 GO:0007049 cell cycle
1.38 1.35e-13 GO:0051649 establishment of localization in cell
1.39 1.85e-13 GO:0010941 regulation of cell death
1.51 2.55e-13 GO:0051726 regulation of cell cycle
1.28 2.82e-13 GO:0048583 regulation of response to stimulus
1.39 3.64e-13 GO:0043067 regulation of programmed cell death
1.39 6.08e-13 GO:0042981 regulation of apoptosis
1.38 8.20e-13 GO:0010646 regulation of cell communication
1.40 9.81e-13 GO:0032774 RNA biosynthetic process
1.42 1.18e-12 GO:0006351 transcription, DNA-dependent
1.21 1.36e-12 GO:0051234 establishment of localization
1.52 1.42e-12 GO:0048666 neuron development
1.41 2.39e-12 GO:0050793 regulation of developmental process
1.56 2.47e-12 GO:0000904 cell morphogenesis involved in differentiation
1.42 2.48e-12 GO:0016265 death
1.43 3.34e-12 GO:0051128 regulation of cellular component organization
1.36 3.94e-12 GO:0044248 cellular catabolic process
1.39 4.30e-12 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.57 4.74e-12 GO:0072358 cardiovascular system development
1.57 4.74e-12 GO:0072359 circulatory system development
1.28 5.13e-12 GO:0007166 cell surface receptor linked signaling pathway
1.51 5.59e-12 GO:0000278 mitotic cell cycle
1.41 5.87e-12 GO:0008219 cell death
1.32 8.44e-12 GO:0035556 intracellular signal transduction
1.42 1.08e-11 GO:0016310 phosphorylation
1.31 1.20e-11 GO:0065009 regulation of molecular function
1.48 1.38e-11 GO:0030030 cell projection organization
1.58 1.72e-11 GO:0048667 cell morphogenesis involved in neuron differentiation
1.21 2.08e-11 GO:0006810 transport
1.53 2.11e-11 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.54 2.38e-11 GO:0031175 neuron projection development
1.46 2.46e-11 GO:0045595 regulation of cell differentiation
1.45 3.63e-11 GO:0019220 regulation of phosphate metabolic process
1.45 3.63e-11 GO:0051174 regulation of phosphorus metabolic process
1.26 4.25e-11 GO:0048513 organ development
1.58 4.27e-11 GO:0007409 axonogenesis
1.24 5.03e-11 GO:0042221 response to chemical stimulus
1.37 5.99e-11 GO:0009892 negative regulation of metabolic process
1.47 9.04e-11 GO:0032989 cellular component morphogenesis
1.21 1.46e-10 GO:0009889 regulation of biosynthetic process
1.55 1.74e-10 GO:0048812 neuron projection morphogenesis
1.63 2.14e-10 GO:0007411 axon guidance
1.47 2.22e-10 GO:0000902 cell morphogenesis
1.44 2.23e-10 GO:0042325 regulation of phosphorylation
1.36 2.90e-10 GO:0009605 response to external stimulus
1.38 3.16e-10 GO:0031324 negative regulation of cellular metabolic process
1.21 3.30e-10 GO:0031326 regulation of cellular biosynthetic process
1.31 3.32e-10 GO:0051239 regulation of multicellular organismal process
1.37 4.12e-10 GO:0010605 negative regulation of macromolecule metabolic process
1.40 4.24e-10 GO:0022402 cell cycle process
1.40 5.93e-10 GO:0046907 intracellular transport
1.36 1.43e-09 GO:0042127 regulation of cell proliferation
1.32 1.63e-09 GO:0044085 cellular component biogenesis
1.45 1.85e-09 GO:0009887 organ morphogenesis
1.21 2.01e-09 GO:0006950 response to stress
1.21 2.20e-09 GO:0010468 regulation of gene expression
1.42 2.30e-09 GO:0022403 cell cycle phase
1.42 2.70e-09 GO:0010628 positive regulation of gene expression
1.50 2.99e-09 GO:0007010 cytoskeleton organization
1.44 3.37e-09 GO:0001932 regulation of protein phosphorylation
1.55 3.49e-09 GO:0051247 positive regulation of protein metabolic process
1.35 3.53e-09 GO:0032879 regulation of localization
1.40 4.30e-09 GO:0006468 protein phosphorylation
1.49 4.72e-09 GO:0048858 cell projection morphogenesis
1.57 5.50e-09 GO:0044419 interspecies interaction between organisms
1.40 5.69e-09 GO:0012501 programmed cell death
1.41 5.92e-09 GO:0009790 embryo development
1.48 7.22e-09 GO:0032990 cell part morphogenesis
1.59 9.32e-09 GO:0045597 positive regulation of cell differentiation
1.21 9.40e-09 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.11 9.59e-09 GO:0050896 response to stimulus
1.28 1.05e-08 GO:0009056 catabolic process
1.33 1.08e-08 GO:0022607 cellular component assembly
1.38 1.19e-08 GO:0051173 positive regulation of nitrogen compound metabolic process
1.39 1.59e-08 GO:2000026 regulation of multicellular organismal development
1.61 1.66e-08 GO:0051325 interphase
1.19 1.77e-08 GO:0051171 regulation of nitrogen compound metabolic process
1.38 1.91e-08 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.20 2.34e-08 GO:0010556 regulation of macromolecule biosynthetic process
1.41 2.39e-08 GO:0051254 positive regulation of RNA metabolic process
1.36 2.97e-08 GO:0031328 positive regulation of cellular biosynthetic process
1.53 3.31e-08 GO:0032270 positive regulation of cellular protein metabolic process
1.39 3.35e-08 GO:0006915 apoptosis
1.60 3.47e-08 GO:0051329 interphase of mitotic cell cycle
1.49 3.61e-08 GO:0051094 positive regulation of developmental process
1.28 3.68e-08 GO:0033036 macromolecule localization
1.36 4.64e-08 GO:0044093 positive regulation of molecular function
1.35 4.98e-08 GO:0009891 positive regulation of biosynthetic process
1.19 6.44e-08 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.38 6.98e-08 GO:0010557 positive regulation of macromolecule biosynthetic process
1.41 8.34e-08 GO:0009057 macromolecule catabolic process
1.44 1.16e-07 GO:0044265 cellular macromolecule catabolic process
1.39 1.17e-07 GO:0009890 negative regulation of biosynthetic process
1.52 2.35e-07 GO:0090066 regulation of anatomical structure size
1.40 2.38e-07 GO:0045893 positive regulation of transcription, DNA-dependent
1.45 2.56e-07 GO:0043549 regulation of kinase activity
1.40 3.05e-07 GO:0051276 chromosome organization
1.34 3.21e-07 GO:0040011 locomotion
1.38 3.44e-07 GO:0031327 negative regulation of cellular biosynthetic process
1.39 4.03e-07 GO:0010558 negative regulation of macromolecule biosynthetic process
1.28 4.35e-07 GO:0050790 regulation of catalytic activity
1.44 4.78e-07 GO:0007417 central nervous system development
1.46 4.87e-07 GO:0048646 anatomical structure formation involved in morphogenesis
1.54 5.55e-07 GO:0032535 regulation of cellular component size
1.44 6.12e-07 GO:0051338 regulation of transferase activity
1.46 8.16e-07 GO:0060548 negative regulation of cell death
1.43 8.69e-07 GO:0006974 response to DNA damage stimulus
1.60 1.03e-06 GO:0008361 regulation of cell size
1.52 1.17e-06 GO:0010564 regulation of cell cycle process
1.35 1.31e-06 GO:0071844 cellular component assembly at cellular level
1.57 1.39e-06 GO:0001944 vasculature development
1.37 1.67e-06 GO:0009719 response to endogenous stimulus
1.39 1.73e-06 GO:0009725 response to hormone stimulus
1.46 1.77e-06 GO:0043069 negative regulation of programmed cell death
1.56 1.93e-06 GO:0051270 regulation of cellular component movement
1.38 2.01e-06 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.26 2.05e-06 GO:0010033 response to organic substance
1.57 2.46e-06 GO:0007346 regulation of mitotic cell cycle
1.55 2.84e-06 GO:0006366 transcription from RNA polymerase II promoter
1.63 2.89e-06 GO:0048011 nerve growth factor receptor signaling pathway
1.39 3.01e-06 GO:0042060 wound healing
1.58 3.18e-06 GO:0001568 blood vessel development
1.28 3.36e-06 GO:0008104 protein localization
1.45 3.83e-06 GO:0010648 negative regulation of cell communication
1.19 3.97e-06 GO:0051252 regulation of RNA metabolic process
1.53 4.33e-06 GO:0031401 positive regulation of protein modification process
1.45 4.36e-06 GO:0043066 negative regulation of apoptosis
1.43 5.36e-06 GO:0045859 regulation of protein kinase activity
1.35 5.78e-06 GO:0043085 positive regulation of catalytic activity
1.60 7.44e-06 GO:0007507 heart development
1.43 8.03e-06 GO:0008283 cell proliferation
1.55 8.03e-06 GO:0061061 muscle structure development
1.37 1.12e-05 GO:0006259 DNA metabolic process
1.11 1.30e-05 GO:0032501 multicellular organismal process
1.48 1.34e-05 GO:0007420 brain development
1.49 1.42e-05 GO:0043434 response to peptide hormone stimulus
1.48 1.48e-05 GO:0018193 peptidyl-amino acid modification
1.32 1.79e-05 GO:0016192 vesicle-mediated transport
1.43 1.93e-05 GO:0023057 negative regulation of signaling
1.57 1.98e-05 GO:0030036 actin cytoskeleton organization
1.52 2.06e-05 GO:0051130 positive regulation of cellular component organization
1.39 2.13e-05 GO:0006935 chemotaxis
1.39 2.13e-05 GO:0042330 taxis
1.18 2.41e-05 GO:0006355 regulation of transcription, DNA-dependent
1.73 3.37e-05 GO:0000082 G1/S transition of mitotic cell cycle
1.38 3.75e-05 GO:0045892 negative regulation of transcription, DNA-dependent
1.36 4.15e-05 GO:0010629 negative regulation of gene expression
1.35 4.31e-05 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.45 5.02e-05 GO:0009792 embryo development ending in birth or egg hatching
1.37 6.04e-05 GO:0051253 negative regulation of RNA metabolic process
1.35 6.11e-05 GO:0051172 negative regulation of nitrogen compound metabolic process
1.40 6.38e-05 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.52 6.39e-05 GO:0015980 energy derivation by oxidation of organic compounds
1.42 6.76e-05 GO:0008285 negative regulation of cell proliferation
1.38 6.93e-05 GO:0009967 positive regulation of signal transduction
1.51 7.57e-05 GO:0035295 tube development
1.53 7.58e-05 GO:0030334 regulation of cell migration
1.42 8.70e-05 GO:0040008 regulation of growth
1.42 8.96e-05 GO:0009968 negative regulation of signal transduction
1.48 9.06e-05 GO:0060284 regulation of cell development
1.19 9.15e-05 GO:0044281 small molecule metabolic process
1.56 1.00e-04 GO:0002009 morphogenesis of an epithelium
1.56 1.14e-04 GO:0071156 regulation of cell cycle arrest
1.55 1.14e-04 GO:0001558 regulation of cell growth
1.44 1.22e-04 GO:0043009 chordate embryonic development
1.36 1.48e-04 GO:0006928 cellular component movement
1.29 1.54e-04 GO:0048584 positive regulation of response to stimulus
1.50 1.55e-04 GO:0010608 posttranscriptional regulation of gene expression
1.37 1.59e-04 GO:0010647 positive regulation of cell communication
1.51 1.88e-04 GO:2000145 regulation of cell motility
1.57 1.91e-04 GO:0000075 cell cycle checkpoint
1.44 2.05e-04 GO:0051301 cell division
1.37 2.14e-04 GO:0007599 hemostasis
1.37 2.17e-04 GO:0043068 positive regulation of programmed cell death
1.41 2.24e-04 GO:0007243 intracellular protein kinase cascade
1.41 2.24e-04 GO:0023014 signal transduction via phosphorylation event
1.36 2.28e-04 GO:0010942 positive regulation of cell death
1.28 2.28e-04 GO:0009888 tissue development
1.49 2.47e-04 GO:0040012 regulation of locomotion
1.46 2.66e-04 GO:0043632 modification-dependent macromolecule catabolic process
1.37 2.72e-04 GO:0019226 transmission of nerve impulse
1.37 2.72e-04 GO:0035637 multicellular organismal signaling
1.36 2.91e-04 GO:0023056 positive regulation of signaling
1.34 2.99e-04 GO:0050878 regulation of body fluid levels
1.46 3.02e-04 GO:0019941 modification-dependent protein catabolic process
1.34 3.03e-04 GO:0071822 protein complex subunit organization
1.36 3.14e-04 GO:0008284 positive regulation of cell proliferation
1.37 3.35e-04 GO:0007596 blood coagulation
1.37 3.35e-04 GO:0050817 coagulation
1.36 3.39e-04 GO:0043065 positive regulation of apoptosis
1.43 3.74e-04 GO:0030163 protein catabolic process
1.67 4.03e-04 GO:0045926 negative regulation of growth
1.55 4.18e-04 GO:0048514 blood vessel morphogenesis
1.48 4.28e-04 GO:0030029 actin filament-based process
1.36 4.64e-04 GO:0070271 protein complex biogenesis
1.40 5.49e-04 GO:0006091 generation of precursor metabolites and energy
1.63 5.50e-04 GO:0031400 negative regulation of protein modification process
1.46 5.70e-04 GO:0000087 M phase of mitotic cell cycle
1.44 6.45e-04 GO:0051603 proteolysis involved in cellular protein catabolic process
1.51 7.16e-04 GO:0050767 regulation of neurogenesis
1.46 7.41e-04 GO:0048285 organelle fission
1.35 8.13e-04 GO:0034613 cellular protein localization
1.43 8.18e-04 GO:0044257 cellular protein catabolic process
1.44 8.41e-04 GO:0006511 ubiquitin-dependent protein catabolic process
1.35 8.78e-04 GO:0070727 cellular macromolecule localization
1.46 9.54e-04 GO:0000280 nuclear division
1.46 9.54e-04 GO:0007067 mitosis
1.46 9.58e-04 GO:0048729 tissue morphogenesis
1.41 9.62e-04 GO:0048598 embryonic morphogenesis
1.41 9.80e-04 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
1.41 9.80e-04 GO:0016568 chromatin modification
1.55 1.04e-03 GO:0045664 regulation of neuron differentiation
1.38 1.12e-03 GO:0016477 cell migration
1.35 1.21e-03 GO:0006461 protein complex assembly
1.26 1.32e-03 GO:0045184 establishment of protein localization
1.44 1.39e-03 GO:0033674 positive regulation of kinase activity
1.66 1.46e-03 GO:0016055 Wnt receptor signaling pathway
1.48 1.54e-03 GO:0045596 negative regulation of cell differentiation
1.63 1.70e-03 GO:0031344 regulation of cell projection organization
1.48 1.72e-03 GO:0051248 negative regulation of protein metabolic process
1.26 1.83e-03 GO:0015031 protein transport
1.34 1.85e-03 GO:0048585 negative regulation of response to stimulus
1.71 1.87e-03 GO:0045792 negative regulation of cell size
1.74 1.88e-03 GO:0061138 morphogenesis of a branching epithelium
1.37 1.91e-03 GO:0032583 regulation of gene-specific transcription
1.38 1.94e-03 GO:0016032 viral reproduction
1.42 1.98e-03 GO:0051347 positive regulation of transferase activity
1.60 2.12e-03 GO:0010552 positive regulation of gene-specific transcription from RNA polymerase II promoter
1.26 2.19e-03 GO:0043933 macromolecular complex subunit organization
2.14 2.25e-03 GO:0045767 regulation of anti-apoptosis
1.69 2.26e-03 GO:0050890 cognition
1.45 2.35e-03 GO:0071900 regulation of protein serine/threonine kinase activity
1.36 2.37e-03 GO:0061024 membrane organization
2.07 2.37e-03 GO:0060070 canonical Wnt receptor signaling pathway
1.30 2.37e-03 GO:0071310 cellular response to organic substance
1.52 2.45e-03 GO:0006916 anti-apoptosis
1.36 2.67e-03 GO:0016044 cellular membrane organization
1.49 2.78e-03 GO:0030168 platelet activation
1.48 3.30e-03 GO:0032269 negative regulation of cellular protein metabolic process
1.51 3.30e-03 GO:0043193 positive regulation of gene-specific transcription
1.43 3.33e-03 GO:0007610 behavior
1.23 3.39e-03 GO:0007154 cell communication
1.53 3.46e-03 GO:0044087 regulation of cellular component biogenesis
1.28 3.78e-03 GO:0065003 macromolecular complex assembly
1.32 3.99e-03 GO:0016071 mRNA metabolic process
1.71 4.07e-03 GO:0007611 learning or memory
2.15 4.69e-03 GO:0000070 mitotic sister chromatid segregation
1.49 4.78e-03 GO:0051129 negative regulation of cellular component organization
1.58 4.82e-03 GO:0010498 proteasomal protein catabolic process
1.58 4.82e-03 GO:0043161 proteasomal ubiquitin-dependent protein catabolic process
1.42 4.87e-03 GO:0045860 positive regulation of protein kinase activity
1.27 5.05e-03 GO:0051049 regulation of transport
1.64 5.23e-03 GO:0042692 muscle cell differentiation
1.40 5.38e-03 GO:0006281 DNA repair
1.42 5.45e-03 GO:0022603 regulation of anatomical structure morphogenesis
1.51 5.55e-03 GO:0000375 RNA splicing, via transesterification reactions
1.40 5.63e-03 GO:0071495 cellular response to endogenous stimulus
1.33 5.68e-03 GO:0006753 nucleoside phosphate metabolic process
1.33 5.68e-03 GO:0009117 nucleotide metabolic process
1.57 5.94e-03 GO:0001525 angiogenesis
1.38 6.37e-03 GO:0060429 epithelium development
1.35 6.63e-03 GO:0007268 synaptic transmission
1.41 6.77e-03 GO:0032940 secretion by cell
1.49 6.91e-03 GO:0045786 negative regulation of cell cycle
1.40 8.17e-03 GO:0051098 regulation of binding
1.31 8.18e-03 GO:0055086 nucleobase, nucleoside and nucleotide metabolic process
1.56 8.27e-03 GO:0006417 regulation of translation
1.43 8.34e-03 GO:0051960 regulation of nervous system development
1.41 8.70e-03 GO:0032870 cellular response to hormone stimulus
1.70 8.87e-03 GO:0006836 neurotransmitter transport
1.65 9.72e-03 GO:0033273 response to vitamin
2.07 1.04e-02 GO:0000819 sister chromatid segregation
1.34 1.10e-02 GO:0000279 M phase
1.53 1.12e-02 GO:0016569 covalent chromatin modification
1.41 1.16e-02 GO:0031667 response to nutrient levels
1.28 1.16e-02 GO:0046483 heterocycle metabolic process
1.68 1.20e-02 GO:0030308 negative regulation of cell growth
1.32 1.28e-02 GO:0001775 cell activation
1.52 1.33e-02 GO:0035239 tube morphogenesis
1.40 1.40e-02 GO:0008380 RNA splicing
1.35 1.46e-02 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.69 1.52e-02 GO:0010720 positive regulation of cell development
1.62 1.62e-02 GO:0001763 morphogenesis of a branching structure
1.39 1.63e-02 GO:0051093 negative regulation of developmental process
1.57 1.67e-02 GO:0031396 regulation of protein ubiquitination
1.39 1.68e-02 GO:0009991 response to extracellular stimulus
1.37 1.74e-02 GO:0012502 induction of programmed cell death
1.82 1.75e-02 GO:0031346 positive regulation of cell projection organization
1.60 1.81e-02 GO:0042391 regulation of membrane potential
1.46 1.81e-02 GO:0071375 cellular response to peptide hormone stimulus
1.52 1.97e-02 GO:0016570 histone modification
1.32 2.01e-02 GO:0048870 cell motility
1.32 2.01e-02 GO:0051674 localization of cell
1.49 2.23e-02 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
1.49 2.23e-02 GO:0000398 nuclear mRNA splicing, via spliceosome
1.56 2.34e-02 GO:0032147 activation of protein kinase activity
1.37 2.41e-02 GO:0006917 induction of apoptosis
1.79 2.65e-02 GO:0007173 epidermal growth factor receptor signaling pathway
1.65 2.67e-02 GO:0042770 signal transduction in response to DNA damage
1.63 2.68e-02 GO:0007265 Ras protein signal transduction
1.23 2.77e-02 GO:0009611 response to wounding
1.23 2.84e-02 GO:0042592 homeostatic process
1.58 3.20e-02 GO:0008286 insulin receptor signaling pathway
1.71 3.47e-02 GO:0031397 negative regulation of protein ubiquitination
1.82 3.91e-02 GO:0051147 regulation of muscle cell differentiation
1.63 3.92e-02 GO:0000084 S phase of mitotic cell cycle
1.29 4.21e-02 GO:0019725 cellular homeostasis
1.49 4.27e-02 GO:0010562 positive regulation of phosphorus metabolic process
1.49 4.27e-02 GO:0045937 positive regulation of phosphate metabolic process
1.60 4.31e-02 GO:0010975 regulation of neuron projection development
1.37 4.33e-02 GO:0033043 regulation of organelle organization
2.11 4.57e-02 GO:0045768 positive regulation of anti-apoptosis
1.58 4.72e-02 GO:0048705 skeletal system morphogenesis
1.34 4.75e-02 GO:0044271 cellular nitrogen compound biosynthetic process
1.55 4.80e-02 GO:0015931 nucleobase, nucleoside, nucleotide and nucleic acid transport
1.60 4.90e-02 GO:0050657 nucleic acid transport
1.60 4.90e-02 GO:0050658 RNA transport
1.60 4.90e-02 GO:0051236 establishment of RNA localization

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.17 1.20e-87 GO:0044424 intracellular part
1.16 3.42e-84 GO:0005622 intracellular
1.22 9.25e-75 GO:0005737 cytoplasm
1.16 4.11e-55 GO:0043226 organelle
1.16 1.88e-54 GO:0043229 intracellular organelle
1.18 4.48e-53 GO:0043227 membrane-bounded organelle
1.18 1.29e-52 GO:0043231 intracellular membrane-bounded organelle
1.23 1.20e-45 GO:0044444 cytoplasmic part
1.22 3.20e-36 GO:0044422 organelle part
1.22 4.70e-36 GO:0044446 intracellular organelle part
1.21 3.58e-33 GO:0005634 nucleus
1.39 1.08e-31 GO:0005829 cytosol
1.36 9.00e-31 GO:0031974 membrane-enclosed lumen
1.36 1.45e-30 GO:0070013 intracellular organelle lumen
1.36 7.73e-30 GO:0043233 organelle lumen
1.37 2.62e-29 GO:0044428 nuclear part
1.05 7.33e-28 GO:0005623 cell
1.05 1.12e-27 GO:0044464 cell part
1.38 8.57e-27 GO:0031981 nuclear lumen
1.25 3.63e-19 GO:0043234 protein complex
1.22 3.68e-19 GO:0032991 macromolecular complex
1.37 1.76e-17 GO:0005654 nucleoplasm
1.23 2.59e-14 GO:0043228 non-membrane-bounded organelle
1.23 2.59e-14 GO:0043232 intracellular non-membrane-bounded organelle
1.29 2.18e-08 GO:0000267 cell fraction
1.48 5.66e-08 GO:0043005 neuron projection
1.41 6.47e-08 GO:0005694 chromosome
1.32 1.43e-07 GO:0005626 insoluble fraction
1.35 2.79e-07 GO:0044451 nucleoplasm part
1.19 5.59e-07 GO:0031090 organelle membrane
1.22 8.59e-07 GO:0005856 cytoskeleton
1.31 1.92e-06 GO:0005624 membrane fraction
1.32 5.76e-06 GO:0031967 organelle envelope
1.63 7.36e-06 GO:0031252 cell leading edge
1.27 9.28e-06 GO:0005794 Golgi apparatus
1.31 1.18e-05 GO:0031975 envelope
1.22 1.37e-05 GO:0005739 mitochondrion
1.17 1.80e-05 GO:0044459 plasma membrane part
1.88 1.87e-05 GO:0042470 melanosome
1.88 1.87e-05 GO:0048770 pigment granule
1.20 2.19e-05 GO:0012505 endomembrane system
1.32 2.23e-05 GO:0015630 microtubule cytoskeleton
1.36 3.15e-05 GO:0005730 nucleolus
1.26 8.08e-05 GO:0042995 cell projection
1.29 8.18e-05 GO:0031988 membrane-bounded vesicle
1.36 8.79e-05 GO:0044427 chromosomal part
1.30 1.35e-04 GO:0044429 mitochondrial part
1.57 1.68e-04 GO:0030424 axon
1.26 2.89e-04 GO:0031982 vesicle
1.28 3.07e-04 GO:0016023 cytoplasmic membrane-bounded vesicle
1.55 4.48e-04 GO:0005819 spindle
1.26 4.50e-04 GO:0031410 cytoplasmic vesicle
1.43 5.43e-04 GO:0015629 actin cytoskeleton
1.60 1.21e-03 GO:0000793 condensed chromosome
1.33 1.45e-03 GO:0005768 endosome
1.19 2.97e-03 GO:0005887 integral to plasma membrane
1.85 3.29e-03 GO:0031256 leading edge membrane
1.19 3.83e-03 GO:0031226 intrinsic to plasma membrane
1.35 4.63e-03 GO:0048471 perinuclear region of cytoplasm
1.31 5.35e-03 GO:0005740 mitochondrial envelope
1.47 6.33e-03 GO:0030425 dendrite
1.54 7.32e-03 GO:0000775 chromosome, centromeric region
1.69 7.67e-03 GO:0000776 kinetochore
1.42 8.02e-03 GO:0016323 basolateral plasma membrane
1.43 8.21e-03 GO:0016604 nuclear body
1.43 1.07e-02 GO:0000228 nuclear chromosome
1.67 1.16e-02 GO:0001726 ruffle
1.57 1.41e-02 GO:0044455 mitochondrial membrane part
1.40 1.79e-02 GO:0005635 nuclear envelope
1.29 1.89e-02 GO:0031966 mitochondrial membrane
1.19 2.14e-02 GO:0044430 cytoskeletal part
1.25 2.25e-02 GO:0044431 Golgi apparatus part
1.30 2.46e-02 GO:0045202 synapse
1.48 2.57e-02 GO:0031300 intrinsic to organelle membrane
1.52 2.62e-02 GO:0031301 integral to organelle membrane
1.58 3.07e-02 GO:0030055 cell-substrate junction
1.60 3.65e-02 GO:0005925 focal adhesion
1.58 3.99e-02 GO:0005924 cell-substrate adherens junction

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.29 6.21e-101 GO:0005515 protein binding
1.13 2.76e-64 GO:0005488 binding
1.16 2.66e-17 GO:0003824 catalytic activity
1.45 1.32e-13 GO:0019899 enzyme binding
1.41 1.90e-13 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.24 5.49e-13 GO:0000166 nucleotide binding
1.26 5.07e-12 GO:0035639 purine ribonucleoside triphosphate binding
1.26 6.56e-12 GO:0032553 ribonucleotide binding
1.26 6.56e-12 GO:0032555 purine ribonucleotide binding
1.26 8.58e-12 GO:0017076 purine nucleotide binding
1.42 2.42e-11 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.28 3.10e-11 GO:0005524 ATP binding
1.28 3.31e-11 GO:0032559 adenyl ribonucleotide binding
1.40 4.44e-11 GO:0016301 kinase activity
1.28 5.03e-11 GO:0030554 adenyl nucleotide binding
1.35 1.36e-10 GO:0030528 transcription regulator activity
1.24 3.16e-09 GO:0016740 transferase activity
1.41 8.35e-09 GO:0004672 protein kinase activity
1.39 4.35e-08 GO:0046983 protein dimerization activity
1.36 5.19e-08 GO:0042802 identical protein binding
1.37 8.93e-08 GO:0043565 sequence-specific DNA binding
1.30 2.10e-07 GO:0001071 nucleic acid binding transcription factor activity
1.30 2.10e-07 GO:0003700 sequence-specific DNA binding transcription factor activity
1.48 3.59e-07 GO:0000988 protein binding transcription factor activity
1.48 3.59e-07 GO:0000989 transcription factor binding transcription factor activity
1.45 4.38e-07 GO:0019904 protein domain specific binding
1.48 5.38e-07 GO:0003712 transcription cofactor activity
1.52 6.11e-07 GO:0016563 transcription activator activity
1.42 3.63e-06 GO:0004674 protein serine/threonine kinase activity
1.53 9.02e-06 GO:0032403 protein complex binding
1.46 1.62e-04 GO:0008134 transcription factor binding
1.55 1.74e-04 GO:0019901 protein kinase binding
1.51 1.77e-04 GO:0019900 kinase binding
1.33 3.05e-04 GO:0008092 cytoskeletal protein binding
1.12 4.95e-04 GO:0003676 nucleic acid binding
1.62 6.93e-04 GO:0003714 transcription corepressor activity
1.76 4.93e-03 GO:0019199 transmembrane receptor protein kinase activity
1.32 5.67e-03 GO:0042803 protein homodimerization activity
1.13 6.35e-03 GO:0003677 DNA binding
1.67 7.31e-03 GO:0005057 receptor signaling protein activity
1.46 9.76e-03 GO:0000975 regulatory region DNA binding
1.46 9.76e-03 GO:0001067 regulatory region nucleic acid binding
1.46 9.76e-03 GO:0044212 transcription regulatory region DNA binding
1.23 1.20e-02 GO:0003723 RNA binding
1.46 1.64e-02 GO:0010843 promoter binding
1.62 1.83e-02 GO:0019838 growth factor binding
1.29 2.05e-02 GO:0030695 GTPase regulator activity
1.46 2.74e-02 GO:0003682 chromatin binding
1.69 4.18e-02 GO:0031625 ubiquitin protein ligase binding